Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPOR | P19235 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496431 | 0.85 | TTR (0.39) | ALDH1A1CYP3A4EPORTTRPTGS1 | |
| SCHEMBL29110082 | 0.85 | EPOR (0.40) | ALDH1A1CYP3A4EPORTTRPTGS1 | |
| SCHEMBL9496444 | 0.85 | TTR (0.39) | ALDH1A1CYP3A4EPORTTRPTGS1 | |
| SCHEMBL29110079 | 0.85 | EPOR (0.40) | ALDH1A1CYP3A4EPORTTRPTGS1 | |
| SCHEMBL10446493 | 0.80 | EPOR (0.38) | EPORTTRPTGS1ALOX5ALOX5AP | |
| SCHEMBL29110085 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TTRMAPTMAPK1 | |
| SCHEMBL10489449 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TTRMAPTMAPK1 | |
| SCHEMBL10489447 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TTRMAPTMAPK1 | |
| SCHEMBL30620008 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TTRMAPTMAPK1 | |
| SCHEMBL3159523 | 0.80 | KDM4E (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0279531-A2 | Process and intermediates for the preparation of insecticidally active compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |