Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | DGKA | P23743 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | DGKG | P49619 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9630532 | 0.99 | MAPT (0.55) | MAPTDGKAHIF1ADGKGTP53 | |
| Hydrochloric Acid SCHEMBL9874132 | 0.81 | HTR2A (0.57) | MAPTHIF1ATP53CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9871592 | 0.76 | HTR2A (0.47) | MAPTCYP2C9ALDH1A1LMNACYP2C19 | |
| SCHEMBL9253169 | 0.73 | MAPT (0.54) | MAPTDGKAHIF1ADGKGTP53 | |
| Hydrochloric Acid SCHEMBL9382804 | 0.72 | MAPT (0.47) | MAPTDGKAHIF1ADGKGTP53 | |
| Diacylglycerol Kinase Inhibitor Ii SCHEMBL317664 | 0.72 | MAPT (1.00) | MAPTDGKAHIF1ADGKGTP53 | |
| SCHEMBL9632595 | 0.71 | MAPT (0.48) | MAPTDGKAHIF1ADGKGTP53 | |
| SCHEMBL8597120 | 0.71 | HTR1A (0.51) | NPC1PKMRAB9ADRD2HTR2A | |
| SCHEMBL29703239 | 0.71 | TDP1 (0.69) | MAPTALDH1A1LMNATDP1KDM4E | |
| SCHEMBL7894526 | 0.71 | TDP1 (0.69) | MAPTALDH1A1LMNATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | claimed |