Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652941 | 0.81 | KCNA5 (0.47) | HTTLMNAPOLBMEN1CYP1A2 | |
| SCHEMBL15955591 | 0.79 | ALOX15 (0.50) | HTTPOLBKMT2AHPGDALDH1A1 | |
| SCHEMBL9561666 | 0.78 | NQO1 (0.50) | ACACBCNR2LMNAMEN1KMT2A | |
| SCHEMBL10555386 | 0.78 | NQO1 (0.50) | ACACBCNR2LMNAMEN1KMT2A | |
| SCHEMBL9560409 | 0.78 | NQO1 (0.50) | ACACBCNR2LMNAMEN1KMT2A | |
| SCHEMBL17404832 | 0.76 | KDM4E (0.43) | HTTLMNAPOLBMEN1KMT2A | |
| SCHEMBL27598638 | 0.75 | ACACB (0.48) | HTTACACBCNR2LMNAPLK1 | |
| SCHEMBL7922514 | 0.74 | NQO1 (0.50) | ACACBCNR2LMNAMEN1KMT2A | |
| SCHEMBL4332048 | 0.74 | NQO1 (0.50) | ACACBCNR2LMNAMEN1KMT2A | |
| SCHEMBL4332044 | 0.74 | NQO1 (0.50) | ACACBCNR2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |