SCHEMBL9804424

SCHEMBL9804424

CCOc1c(F)cc(C(CCCc2cccc(Oc3ccccc3)c2)C(F)(F)F)cc1F

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 4/20 0.44
FDFT1 P37268 15/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804252 0.88 FDFT1 (0.35) CETPFDFT1
SCHEMBL7934937 0.88 CETP (0.43) CETPFDFT1
SCHEMBL9804660 0.87 CETP (0.44) CETPFDFT1
SCHEMBL7931627 0.87 CETP (0.49) CETPFDFT1
SCHEMBL9561404 0.83 CETP (0.44) CETP
SCHEMBL9561317 0.83 CETP (0.44) CETP
SCHEMBL7930475 0.83 FDFT1 (0.52) CETPFDFT1
SCHEMBL9804456 0.81 FDFT1 (0.54) CETPFDFT1
SCHEMBL9804670 0.81 FDFT1 (0.56) CETPFDFT1
SCHEMBL9804359 0.80 KDM4E (0.50) CETPFDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0240121-B1 DIPHENYL ETHER DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-04-17 EP disclosed
EP-0390228-A2 Chemical intermediates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-03 EP disclosed
US-4791139-A Diphenyl ether derivatives and their use as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-13 US disclosed
EP-0240121-A2 Diphenyl ether derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-10-07 EP disclosed