Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827324 | 0.80 | NQO1 (0.48) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL9570747 | 0.79 | NQO1 (0.47) | NQO1TSHRTDP1ACACBCYP1A1 | |
| SCHEMBL4332044 | 0.78 | NQO1 (0.50) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL4332048 | 0.78 | NQO1 (0.50) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL9561666 | 0.78 | NQO1 (0.50) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL9560409 | 0.78 | NQO1 (0.50) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL7922514 | 0.78 | NQO1 (0.50) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL10555386 | 0.78 | NQO1 (0.50) | NQO1TSHRTDP1ACACBPARP10 | |
| SCHEMBL9804366 | 0.77 | NQO1 (0.38) | NQO1TSHRTDP1ACACBCYP1A1 | |
| SCHEMBL9804375 | 0.77 | NQO1 (0.38) | NQO1TSHRTDP1ACACBCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1019109-B | The insect-killing composition that contains diphenyl ether derivatives pesticide compound | ICI PLC (GB) | 1992-11-18 | — | — | CN | disclosed |
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |