SCHEMBL9570747

SCHEMBL9570747

CCOc1ccc(C(C=O)C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.47
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ACACB O00763 5/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
MAOB P27338 1/20 0.39
PARP10 Q53GL7 1/20 0.39
RELA Q04206 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CNR2 P34972 1/20 0.38
LMNA P02545 1/20 0.38
LTA4H P09960 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570646 0.87 CA12 (0.41) ACACBCYP1A1CYP1B1CA12CA1
SCHEMBL9570869 0.81 ALDH1A1 (0.44) TSHRTDP1CA12CA1CA2
SCHEMBL9570650 0.81 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL9804428 0.79 NQO1 (0.45) NQO1TSHRTDP1ACACBCYP1A1
SCHEMBL9570578 0.78 ALDH1A3 (0.50) ACACBPARP10CNR2ALDH1A1POLB
SCHEMBL9570882 0.77 PDE2A (0.42) MAOBALDH1A1
SCHEMBL9570843 0.77 TSHR (0.41) TSHRTDP1CA2LMNAAKR1C3
SCHEMBL9570833 0.77 KDM1A (0.40) ACACBLMNAALDH1A1POLB
SCHEMBL15330491 0.77 NQO1 (0.56) NQO1TSHRTDP1ACACBPARP10
SCHEMBL9570620 0.76 ERN1 (0.43) TSHRTDP1RELALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed