SCHEMBL9804430

SCHEMBL9804430

CCCCO[SiH](OCCCC)C(CC)CCOCC1CO1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.58
ALDH1A1 P00352 4/20 0.51
TDP1 Q9NUW8 1/20 0.51
TSHR P16473 2/20 0.43
PDK1 Q15118 1/20 0.34
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10401716 0.91 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL7688097 0.82 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1564440 0.80 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1TDP1TSHRPDK1
SCHEMBL5833981 0.78 ADRB2 (0.32)
SCHEMBL9804581 0.77 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRPDK1
SCHEMBL28561105 0.77 SMN1; SMN2 (0.79) SMN1; SMN2ALDH1A1TDP1TSHRPDK1
SCHEMBL29089 0.76
SCHEMBL7969662 0.76
SCHEMBL2632267 0.76
SCHEMBL19125484 0.75 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1TDP1TSHRPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997738-A Electrophotographic photoreceptor having silicate with perfluoroalkyl groups in protective layer SHINDENGEN ELECTRIC MANUFACTURING CO., LTD. (JP) 1991-03-05 US disclosed