Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | CYBB | P04839 | 2/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613289 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL2604929 | 0.89 | NPC1 (0.61) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL9804533 | 0.85 | MAPT (0.56) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL18774386 | 0.84 | MAPT (0.59) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL7328510 | 0.80 | CHRM5 (0.46) | SMN1; SMN2MAPTCYBBNOX4 | |
| SCHEMBL9804528 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL10386782 | 0.78 | CYP2A6 (0.50) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL9551577 | 0.77 | MEN1 (0.42) | NPC1MEN1KMT2ACYBBNOX4 | |
| SCHEMBL9807477 | 0.77 | MAPT (0.46) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL9551576 | 0.77 | MEN1 (0.42) | NPC1MEN1KMT2ACYBBNOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290591-B1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS | MERCK PATENT GmbH (DE) | 1991-03-13 | — | — | EP | disclosed |
| EP-0290591-A1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS. | MERCK PATENT GMBH (DE) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988004305-A1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-06-16 | — | — | WO | disclosed |