Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 2/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313729 | 0.89 | CALM1 (0.58) | KDM4EGAAMAPTJAK2POLB | |
| SCHEMBL10870748 | 0.86 | KDM4E (0.43) | KDM4EGAAMAPTJAK2POLB | |
| SCHEMBL10870265 | 0.86 | KDM4E (0.43) | KDM4EGAAMAPTJAK2POLB | |
| SCHEMBL3050270 | 0.85 | CNR2 (0.46) | KDM4EGAAMAPTJAK2POLB | |
| SCHEMBL10906000 | 0.83 | PTPN1 (0.54) | BCL2BCL2L1 | |
| Butane SCHEMBL27554305 | 0.82 | CNR2 (0.44) | KDM4EGAAMAPTJAK2POLB | |
| SCHEMBL30768176 | 0.81 | CALM1 (0.55) | KDM4ECALM1NQO1ALDH1A1HPGD | |
| SCHEMBL9190942 | 0.81 | CALM1 (0.55) | KDM4EGAAMAPTJAK2POLB | |
| SCHEMBL24505329 | 0.81 | KDM4E (0.45) | KDM4EGAAMAPTJAK2POLB | |
| SCHEMBL27967513 | 0.80 | KDM4E (0.44) | KDM4EGAAMAPTJAK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186255-B1 | PROCESS FOR PREPARING BENZYL SUBSTITUTED PHENOLS, DIBENZYLPHENOLIC COMPOUNDS, AND THE ANTIOXIDANT USE OF SUCH PHENOLS | ETHYL CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0186255-A2 | Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols | ETHYL CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |