Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922514 | 0.79 | NQO1 (0.50) | NQO1KMT2AMEN1LMNATDP1 | |
| SCHEMBL7932190 | 0.77 | APP (0.40) | KMT2AMEN1LMNAKDM4EALDH1A1 | |
| SCHEMBL9560441 | 0.75 | NQO1 (0.36) | NQO1KMT2AMEN1LMNATDP1 | |
| SCHEMBL7931627 | 0.73 | CETP (0.49) | LTA4H | |
| SCHEMBL4332048 | 0.72 | NQO1 (0.50) | NQO1KMT2AMEN1LMNATDP1 | |
| SCHEMBL4332044 | 0.72 | NQO1 (0.50) | NQO1KMT2AMEN1LMNATDP1 | |
| SCHEMBL10555386 | 0.72 | NQO1 (0.50) | NQO1KMT2AMEN1LMNATDP1 | |
| SCHEMBL9561666 | 0.72 | NQO1 (0.50) | NQO1KMT2AMEN1LMNATDP1 | |
| SCHEMBL9560409 | 0.72 | NQO1 (0.50) | NQO1KMT2AMEN1LMNATDP1 | |
| SCHEMBL9804313 | 0.72 | SLC5A2 (0.40) | KMT2AMEN1LMNAL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |