Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 2/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804440 | 0.84 | SLC7A5 (0.41) | CNR2 | |
| SCHEMBL10646572 | 0.84 | SLC5A2 (0.39) | SLC5A2SLC5A1SIGMAR1CNR2KMT2A | |
| SCHEMBL10651447 | 0.84 | SLC5A2 (0.39) | SLC5A2SLC5A1SIGMAR1CNR2KMT2A | |
| SCHEMBL9560920 | 0.83 | SLC5A2 (0.40) | SLC5A2SLC5A1CNR2KMT2AMEN1 | |
| SCHEMBL407786 | 0.83 | LTA4H (0.41) | SIGMAR1CNR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL7931627 | 0.81 | CETP (0.49) | FFAR1 | |
| SCHEMBL10649169 | 0.76 | SLC5A2 (0.39) | SLC5A2SLC5A1SIGMAR1KMT2AMEN1 | |
| SCHEMBL7931623 | 0.75 | KCNH2 (0.41) | L3MBTL1MAPK1 | |
| SCHEMBL9560866 | 0.75 | FFAR1 (0.41) | SLC5A2SLC5A1DHFRFFAR1 | |
| SCHEMBL10651769 | 0.75 | SLC5A2 (0.39) | SLC5A2SLC5A1SIGMAR1KMT2ADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |