Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804632 | 1.00 | GRIN2B (0.38) | GRIN2BTRPV1SLC6A4CYP11B1CYP11B2 | |
| SCHEMBL9804249 | 0.88 | RELA (0.39) | MAPTSMN1; SMN2 | |
| SCHEMBL9804536 | 0.88 | RELA (0.39) | MAPTSMN1; SMN2 | |
| SCHEMBL9804405 | 0.85 | SLC6A4 (0.38) | GRIN2BTRPV1SLC6A4CYP11B1CYP11B2 | |
| SCHEMBL9804408 | 0.85 | SLC6A4 (0.38) | GRIN2BTRPV1SLC6A4CYP11B1CYP11B2 | |
| SCHEMBL9494663 | 0.81 | PARP10 (0.36) | GRIN2BTRPV1SLC6A4MAPK14 | |
| SCHEMBL9494665 | 0.81 | PARP10 (0.36) | GRIN2BTRPV1SLC6A4MAPK14 | |
| SCHEMBL9492708 | 0.76 | MAPK14 (0.42) | GRIN2BMAPK14 | |
| SCHEMBL9492710 | 0.76 | MAPK14 (0.42) | GRIN2BMAPK14 | |
| SCHEMBL9491929 | 0.76 | PARP10 (0.34) | GRIN2BTRPV1SLC6A4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |