Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31595661 | 0.87 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL1288464 | 0.87 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL2915225 | 0.75 | MAPT (0.54) | KMT2AMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL14886220 | 0.73 | CSNK1A1 (0.53) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL51007 | 0.71 | ADRA2A (0.54) | KMT2AMAPTMEN1SMN1; SMN2IDO1 | |
| SCHEMBL8118221 | 0.71 | ADRA2A (0.50) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL31429565 | 0.71 | ADRA2A (0.50) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL7397776 | 0.71 | MAPT (0.50) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL597104 | 0.71 | ADRA2A (0.50) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28957351 | 0.70 | ADRA2A (0.56) | KMT2AMAPTMEN1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059607-A | Suppresses vomiting induced by anti-cancer agents | ONO-PHARMACEUTICAL CO., LTD. (JP) | 1991-10-22 | — | — | US | disclosed |