Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | APLNR | P35414 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831262 | 0.86 | KDM4E (0.64) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL28191688 | 0.85 | KDM4E (0.63) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL25988241 | 0.83 | KDM4E (0.61) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL21587706 | 0.82 | KDM4E (0.64) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL2895893 | 0.82 | ALDH1A1 (0.55) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL392360 | 0.82 | CYP1A2 (0.62) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL21587657 | 0.81 | KDM4E (0.53) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL2226923 | 0.80 | ALDH1A1 (0.62) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL31263175 | 0.80 | KDM4E (0.52) | KDM4EAPLNRMAPK1ALDH1A1TSHR | |
| SCHEMBL30657133 | 0.80 | KDM4E (0.59) | KDM4EAPLNRMAPK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126709-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AZETIDINONES | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| US-4614614-A | Process for the manufacture of optically active azetidinones | CIBA-GEIGY CORPORATION (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0126709-A1 | Process for the preparation of optically active azetidinones | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |