⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405874 | 0.45 | — | — | |
| SCHEMBL12703368 | 0.45 | — | — | |
| SCHEMBL129408 | 0.45 | — | — | |
| SCHEMBL7009257 | 0.42 | — | — | |
| SCHEMBL12703772 | 0.42 | — | — | |
| SCHEMBL676625 | 0.42 | — | — | |
| Iodide SCHEMBL11281817 | 0.40 | ALDH1A1 (0.57) | — | |
| SCHEMBL2178472 | 0.38 | — | — | |
| SCHEMBL7014344 | 0.38 | — | — | |
| SCHEMBL5134172 | 0.38 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378936-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2024-06-05 | — | — | EP | claimed |
| CN-115677667-A | Bifunctional chimera heterocyclic compound and application thereof as androgen receptor degrading agent | 海创药业股份有限公司 | 2023-02-03 | — | — | CN | claimed |
| US-4287193-A | ANTIBIOTIC DERIVATIVES OF CEPHALOSPORANIC ACID | ROUSSEL UCLAF (FR) | 1981-09-01 | — | — | US | claimed |
| EP-4378936-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2024-06-05 | — | — | EP | disclosed |
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |
| US-5057512-A | Bactericides | Uclaf, Roussel (FR) | 1991-10-15 | — | — | US | disclosed |
| US-4900728-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1990-02-13 | — | — | US | disclosed |
| US-4374834-A | CEPHEM ANTIBIOTICS | Uclaf, Roussel (FR) | 1983-02-22 | — | — | US | disclosed |
| EP-0002774-B1 | PROCESS FOR ACYLATING 7AMINOCEPHEM DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-23 | — | — | EP | disclosed |
| US-4287193-A | ANTIBIOTIC DERIVATIVES OF CEPHALOSPORANIC ACID | ROUSSEL UCLAF (FR) | 1981-09-01 | — | — | US | disclosed |
| EP-0002774-A1 | Process for acylating 7aminocephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |