Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573985 | 0.61 | TP53 (0.30) | CYP3A4MAPTLMNATSHRMAPK1 | |
| SCHEMBL9804971 | 0.60 | — | — | |
| Aldrin SCHEMBL5933947 | 0.57 | CYP3A4 (1.00) | CYP3A4MAPTLMNATSHRMAPK1 | |
| Aldrin SCHEMBL22946166 | 0.57 | CYP3A4 (1.00) | CYP3A4MAPTLMNATSHRMAPK1 | |
| Aldrin SCHEMBL18376 | 0.57 | CYP3A4 (1.00) | CYP3A4MAPTLMNATSHRMAPK1 | |
| Aldrin SCHEMBL5933946 | 0.57 | CYP3A4 (1.00) | CYP3A4MAPTLMNATSHRMAPK1 | |
| Aldrin SCHEMBL119263 | 0.57 | CYP3A4 (1.00) | CYP3A4MAPTLMNATSHRMAPK1 | |
| SCHEMBL6469263 | 0.55 | CYP3A4 (0.32) | CYP3A4MAPT | |
| SCHEMBL8176504 | 0.54 | MEN1 (0.43) | TSHR | |
| SCHEMBL14051318 | 0.53 | TSHR (0.39) | CYP3A4MAPTLMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994535-A | Molding material | HERCULES INCORPORATED (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0283719-A2 | Metathesis polymerized cross-linked halogen-containing copolymer | HERCULES INCORPORATED (US) | 1988-09-28 | — | — | EP | disclosed |