Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477476 | 0.79 | DDB1 (0.41) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL11477485 | 0.79 | DDB1 (0.41) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL11477495 | 0.79 | DDB1 (0.41) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL9804832 | 0.76 | DDB1 (0.44) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL8844240 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL8843800 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL9804969 | 0.76 | DDB1 (0.41) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL9805078 | 0.76 | DDB1 (0.41) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL10807051 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL10806458 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CHRM2OPRM1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057512-A | Bactericides | Uclaf, Roussel (FR) | 1991-10-15 | — | — | US | disclosed |
| US-4900728-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1990-02-13 | — | — | US | disclosed |