Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL9804816 | 0.93 | CYP11B2 (0.41) | CYP11B2HSD11B1CYP3A4IDO1TDO2 | |
| SCHEMBL2822478 | 0.89 | CYP11B2 (0.49) | CYP11B2HSD11B1CYP3A4IDO1TDO2 | |
| SCHEMBL10646410 | 0.88 | CYP11B2 (0.45) | CYP11B2HSD11B1CYP3A4IDO1TDO2 | |
| SCHEMBL2817700 | 0.87 | CYP11B2 (0.43) | CYP11B2HSD11B1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10483522 | 0.87 | CYP11B2 (0.43) | CYP11B2HSD11B1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9493435 | 0.87 | CYP11B2 (0.43) | CYP11B2HSD11B1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9493247 | 0.87 | CYP11B2 (0.43) | CYP11B2HSD11B1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9804994 | 0.87 | CYP11B2 (0.46) | CYP11B2HSD11B1CYP3A4IDO1TDO2 | |
| SCHEMBL2820351 | 0.86 | CYP11B2 (0.41) | CYP11B2HSD11B1CYP3A4IDO1TDO2 | |
| SCHEMBL2820997 | 0.86 | CYP11B2 (0.41) | CYP11B2HSD11B1CYP3A4IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4878940-A | SELECTIVE, FOR USE WITH CROPS | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-11-07 | — | — | US | claimed |
| EP-0289066-A1 | 1,5-Substituted 1H-imidazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-11-02 | — | — | EP | claimed |
| US-4994103-A | Herbicides; rice, corn | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-02-19 | — | — | US | disclosed |
| US-4878940-A | SELECTIVE, FOR USE WITH CROPS | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-11-07 | — | — | US | disclosed |
| EP-0289066-A1 | 1,5-Substituted 1H-imidazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-11-02 | — | — | EP | disclosed |