Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.55 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805082 | 0.88 | ADK (0.57) | ADKHSPA8HSPA5RXFP1HIF1A | |
| SCHEMBL9805553 | 0.86 | ADK (0.65) | ADKHSPA8HSPA5RXFP1HIF1A | |
| SCHEMBL9805237 | 0.86 | ADK (0.65) | ADKHSPA8HSPA5RXFP1HIF1A | |
| SCHEMBL9805198 | 0.82 | PI4KA (0.49) | ADKHSPA8HSPA5RXFP1ADORA3 | |
| SCHEMBL14028811 | 0.78 | ADK (0.68) | ADKHSPA8HSPA5HIF1AMEN1 | |
| SCHEMBL4867832 | 0.78 | ADK (0.68) | ADKHSPA8HSPA5HIF1AMEN1 | |
| SCHEMBL9805128 | 0.78 | GSK3B (0.49) | ADKRXFP1MEN1ADORA3MAPK1 | |
| SCHEMBL17612673 | 0.76 | ADK (0.65) | ADKHSPA8HSPA5RXFP1HIF1A | |
| SCHEMBL17612669 | 0.76 | ADK (0.65) | ADKHSPA8HSPA5RXFP1HIF1A | |
| SCHEMBL17612652 | 0.76 | ADK (0.65) | ADKHSPA8HSPA5RXFP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041542-A | Antitumor-anticarcinogenic agents | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1991-08-20 | — | — | US | disclosed |