Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | STAT3 | P40763 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 8/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805569 | 1.00 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9805350 | 1.00 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL10471431 | 1.00 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9805333 | 1.00 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9805581 | 1.00 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9805362 | 1.00 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL10471430 | 1.00 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9805542 | 0.99 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9805530 | 0.99 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9805634 | 0.95 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242716-B1 | LIQUID-CRYSTALLINE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-20 | — | — | EP | disclosed |
| US-4898455-A | Pyridine liquid crystalline compounds | HOFFMANN-LA ROCHE INC. (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0242716-A1 | Liquid-crystalline pyridine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-10-28 | — | — | EP | disclosed |