Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587102 | 0.87 | TSHR (0.54) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| Acrylic Acid SCHEMBL2693137 | 0.83 | THRB (0.59) | TSHRTHRBLMNAALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL4855327 | 0.82 | TSHR (0.45) | TSHRTHRBLMNAALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL265149 | 0.82 | THRB (0.52) | TSHRTHRBLMNAALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL27651708 | 0.82 | THRB (0.52) | TSHRTHRBLMNAALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL23825514 | 0.80 | THRB (0.50) | TSHRTHRBLMNAALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL6390284 | 0.80 | TSHR (0.44) | TSHRTHRBLMNAALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL278318 | 0.80 | TSHR (0.44) | TSHRTHRBLMNAALDH1A1ALOX15 | |
| Acrylic Acid SCHEMBL28326460 | 0.80 | THRB (0.50) | TSHRTHRBLMNAALDH1A1ALOX15 | |
| SCHEMBL10150486 | 0.79 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417606-A2 | Method of making highly adsorptive copolymers | DOW CORNING CORPORATION (US) | 1991-03-20 | — | — | EP | disclosed |