Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801842 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL51782 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL11440902 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL9806346 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL8497770 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL9806425 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL9801856 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL8855829 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL8855730 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBEPHX1SPHK1 | |
| SCHEMBL11689950 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBEPHX1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170048-B1 | ALIPHATIC THIOETHERS | CIBA-GEIGY AG (CH) | 1991-04-17 | — | — | EP | disclosed |
| US-4649215-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| EP-0170048-A2 | Aliphatic thioethers | CIBA-GEIGY AG (CH) | 1986-02-05 | — | — | EP | disclosed |