Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530129 | 0.92 | AKR1B10 (0.51) | AKR1B10AKR1A1AKR1B1CDC25BKDM4E | |
| SCHEMBL10531806 | 0.90 | AKR1B10 (0.49) | AKR1B10AKR1A1AKR1B1CDC25BKDM4E | |
| SCHEMBL7113675 | 0.89 | AKR1B10 (0.65) | AKR1B10AKR1A1AKR1B1CDC25BKDM4E | |
| Hydrochloric Acid SCHEMBL10417267 | 0.87 | AKR1B10 (0.63) | AKR1B10AKR1A1AKR1B1CDC25BKDM4E | |
| SCHEMBL9800783 | 0.84 | AKR1B10 (0.57) | AKR1B10AKR1A1AKR1B1CDC25BKDM4E | |
| SCHEMBL10527732 | 0.82 | AKR1B10 (0.67) | AKR1B10AKR1A1AKR1B1CDC25BALDH1A1 | |
| SCHEMBL10527714 | 0.80 | AKR1B10 (0.84) | AKR1B10AKR1A1AKR1B1CDC25BALDH1A1 | |
| SCHEMBL7089895 | 0.78 | AKR1B10 (0.62) | AKR1B10AKR1A1AKR1B1CDC25BHPGD | |
| SCHEMBL10529107 | 0.78 | AKR1B10 (0.48) | AKR1B10AKR1A1AKR1B1CDC25BKDM4E | |
| SCHEMBL5771713 | 0.78 | CDC25B (0.55) | AKR1B10AKR1A1AKR1B1CDC25BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307519-B1 | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4889951-A | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| US-4822904-A | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0182499-B1 | N-(6-METHOXY-5-(PERFLUOROALKYL)-1-NAPHTOLYL)-N-METYLGLYCINES AND THEIR THIONAPHTHOYL ANALOGS | AYERST, MCKENNA AND HARRISON INC. (CA) | 1989-04-12 | — | — | EP | disclosed |
| EP-0307519-A1 | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1989-03-22 | — | — | EP | disclosed |
| EP-0304521-A1 | Perfluoroalkylnaphthalene compounds their preparation and use | ETHYL CORPORATION (US) | 1989-03-01 | — | — | EP | disclosed |
| US-4699993-A | Perfluoroalkylnaphthalene compounds | ETHYL CORPORATION (US) | 1987-10-13 | — | — | US | disclosed |
| US-4604406-A | ALDOSE REDUCTASE INHIBITORS | AYERST, MCKENNA & HARRISON, INC. (CA) | 1986-08-05 | — | — | US | disclosed |
| EP-0182499-A1 | N-(6-methoxy-5-(perfluoroalkyl)-1-naphtolyl)-N-metylglycines and their thionaphthoyl analogs | AYERST, MCKENNA AND HARRISON INC. (CA) | 1986-05-28 | — | — | EP | disclosed |