⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20045078 | 0.81 | LMNA (0.42) | — | |
| SCHEMBL21765513 | 0.79 | LMNA (0.40) | — | |
| SCHEMBL19937328 | 0.78 | — | — | |
| SCHEMBL12976344 | 0.74 | — | — | |
| SCHEMBL16073015 | 0.74 | — | — | |
| SCHEMBL20063962 | 0.74 | — | — | |
| SCHEMBL2123610 | 0.73 | — | — | |
| SCHEMBL21922886 | 0.73 | — | — | |
| SCHEMBL15497901 | 0.73 | — | — | |
| SCHEMBL22985614 | 0.73 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212742-B1 | MANUFACTURE OF OXAZOLIDINES BY THE ALKOXYLATION OF IMINES | AKZO N.V. (NL) | 1991-04-17 | — | — | EP | disclosed |
| EP-0212742-A1 | Manufacture of oxazolidines by the alkoxylation of imines | AKZO N.V. (NL) | 1987-03-04 | — | — | EP | disclosed |