Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806688 | 0.95 | FDPS (0.46) | FDPSS1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL7858698 | 0.76 | CYP1A2 (0.39) | CHRNB2CHRNA4CHRNA7S1PR1S1PR3 | |
| SCHEMBL8711817 | 0.74 | CYP1A2 (0.41) | FDPSS1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL2600077 | 0.72 | CYP1A2 (0.44) | CHRNB2CHRNA4CYP1A2 | |
| SCHEMBL13483932 | 0.72 | CYP1A2 (0.44) | CHRNB2CHRNA4CYP1A2 | |
| SCHEMBL14097725 | 0.72 | CYP1A2 (0.44) | CHRNB2CHRNA4CYP1A2 | |
| SCHEMBL9492716 | 0.72 | S1PR1 (0.45) | FDPSS1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9012787 | 0.71 | FDPS (0.41) | FDPS | |
| SCHEMBL20572945 | 0.70 | FDPS (0.53) | FDPS | |
| SCHEMBL19193755 | 0.70 | FDPS (0.58) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273190-B1 | DIPHOSPHORIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-04-17 | — | — | EP | disclosed |
| US-4971958-A | CALCIUM METABOLISM | BOEHRINGER MANNHEIM GMBH (DE) | 1990-11-20 | — | — | US | disclosed |