Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806880 | 0.95 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL9192073 | 0.91 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL9806834 | 0.91 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL9806794 | 0.91 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL9806819 | 0.91 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL9806785 | 0.91 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL9806797 | 0.91 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL8046916 | 0.91 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL9806816 | 0.91 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL9806767 | 0.91 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244939-B1 | HALOGEN-CONTAINING PYRIDINE COMPOUND AND LIQUID CRYSTAL COMPOSITION | Chisso Corporation (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4781857-A | SWITCHES, FERROELECTRICITY | CHISSO CORPORATION (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0244939-A1 | Halogen-containing pyridine compound and liquid crystal composition | Chisso Corporation (JP) | 1987-11-11 | — | — | EP | disclosed |