SCHEMBL9807142

SCHEMBL9807142

Cc1ccc2cc3ccccc3c3c2c1C=C3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.46
ALDH1A1 P00352 7/20 0.46
HSD17B10 Q99714 6/20 0.46
HPGD P15428 4/20 0.46
FYN P06241 2/20 0.44
ACHE P22303 2/20 0.44
AHR P35869 2/20 0.44
ERBB2 P04626 1/20 0.44
MAOA P21397 1/20 0.44
TSHR P16473 5/20 0.44
CYP2A6 P11509 4/20 0.44
LCK P06239 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
MAPT P10636 1/20 0.41
SLC6A2 P23975 1/20 0.41
HIF1A Q16665 2/20 0.39
CYP1B1 Q16678 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
CYP3A4 P08684 2/20 0.38
TDP1 Q9NUW8 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31494528 0.84 ALDH1A1 (0.56) CYP1A2ALDH1A1HSD17B10HPGDFYN
SCHEMBL4851809 0.82 CYP1A2 (0.45) CYP1A2ALDH1A1HSD17B10HPGDFYN
SCHEMBL4851519 0.79 CYP1A2 (0.46) CYP1A2ALDH1A1HSD17B10HPGDFYN
SCHEMBL21625683 0.75 TSHR (0.42) CYP1A2ALDH1A1HSD17B10HPGDTSHR
SCHEMBL4852113 0.75 ALDH1A1 (0.43) CYP1A2ALDH1A1HSD17B10HPGDFYN
SCHEMBL4851957 0.74 ALDH1A1 (0.54) CYP1A2ALDH1A1HSD17B10HPGDFYN
SCHEMBL26028 0.73 CYP1A2 (0.47) CYP1A2ALDH1A1HSD17B10HPGDFYN
SCHEMBL29562021 0.73 CYP1A2 (0.47) CYP1A2ALDH1A1HSD17B10HPGDFYN
SCHEMBL597744 0.72 CYP1A2 (0.71) CYP1A2ALDH1A1HSD17B10HPGDFYN
SCHEMBL1232448 0.72 CYP1A2 (0.71) CYP1A2ALDH1A1HSD17B10HPGDFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3100005-A None JP disclosed
JP-H03100005-A PREPARATION OF CONDENSED RING COMPOUND POLYMER IDEMITSU KOSAN CO LTD 1991-04-25 JP disclosed