Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615103 | 0.83 | HDAC2 (0.49) | NPC1TDP1MEN1KMT2ACYP2C19 | |
| SCHEMBL7616108 | 0.82 | NPC1 (0.47) | NPC1TDP1MEN1KMT2ACYP2C19 | |
| SCHEMBL7609368 | 0.82 | NPC1 (0.47) | NPC1TDP1MEN1KMT2ACYP2C19 | |
| SCHEMBL6451721 | 0.82 | NPC1 (0.63) | NPC1TDP1MEN1KMT2ACA12 | |
| SCHEMBL6913902 | 0.80 | NPC1 (0.66) | NPC1TDP1MEN1KMT2ACA12 | |
| SCHEMBL7614337 | 0.79 | USP2 (0.46) | NPC1TDP1MEN1KMT2ACYP2C19 | |
| SCHEMBL7617229 | 0.78 | MEN1 (0.61) | NPC1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL793341 | 0.78 | TDP1 (0.63) | TDP1LMNACA12CA1CA2 | |
| SCHEMBL7616877 | 0.78 | NPC1 (0.46) | NPC1TDP1MEN1KMT2ACYP2C19 | |
| SCHEMBL7620687 | 0.72 | NPC1 (0.51) | NPC1LMNARAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068264-A | Adhesives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | claimed |
| US-5068264-A | Adhesives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0394792-A1 | (Meth)acrylic acid derivatives containing formyl piperazine groups | BAYER AG (DE) | 1990-10-31 | — | — | EP | disclosed |