Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807428 | 0.90 | TSHR (0.50) | GSK3AGSK3BALDH1A1TSHRTDP1 | |
| SCHEMBL3806617 | 0.83 | HSD17B10 (0.63) | ALDH1A1TSHRTDP1ALOX15LMNA | |
| SCHEMBL6738366 | 0.82 | TSHR (0.76) | ALDH1A1TSHRTDP1ALOX15LMNA | |
| SCHEMBL7953461 | 0.80 | TSHR (0.58) | ALDH1A1TSHRTDP1ALOX15LMNA | |
| SCHEMBL6646630 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1LMNACNR1 | |
| Iodide SCHEMBL28598177 | 0.80 | TSHR (0.73) | ALDH1A1TSHRTDP1ALOX15LMNA | |
| Iodide SCHEMBL30804629 | 0.80 | TSHR (0.73) | ALDH1A1TSHRTDP1ALOX15LMNA | |
| SCHEMBL28471286 | 0.80 | TSHR (0.73) | ALDH1A1TSHRTDP1ALOX15LMNA | |
| SCHEMBL11392466 | 0.80 | TSHR (0.73) | ALDH1A1TSHRTDP1ALOX15LMNA | |
| SCHEMBL11392461 | 0.80 | TSHR (0.73) | ALDH1A1TSHRTDP1ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994545-A | Polyetherimide | ETHYL CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4990627-A | Polyetherimides and their production | ETHYL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |