SCHEMBL9807438

SCHEMBL9807438

Nc1ccc2nc(O)c(O)nc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.55
KMT2A Q03164 3/20 0.53
TLR9 Q9NR96 2/20 0.53
ATM Q13315 2/20 0.53
MEN1 O00255 2/20 0.50
LMNA P02545 2/20 0.50
HTT P42858 2/20 0.50
F2 P00734 1/20 0.50
CHRM2 P08172 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA2A P08913 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
MAOA P21397 1/20 0.50
DRD1 P21728 1/20 0.50
ACHE P22303 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
OPRM1 P35372 1/20 0.50
DRD3 P35462 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6108994 0.98 PIK3CG (0.53) PIK3CGKMT2ATLR9ATMMEN1
SCHEMBL3480837 0.85 KMT2A (0.67) PIK3CGKMT2ATLR9ATMMEN1
SCHEMBL4586206 0.85 KMT2A (0.67) PIK3CGKMT2ATLR9ATMMEN1
SCHEMBL29922808 0.85 KMT2A (0.67) PIK3CGKMT2ATLR9ATMMEN1
Hydrochloric Acid SCHEMBL7566148 0.82 KMT2A (0.64) PIK3CGKMT2ATLR9ATMMEN1
SCHEMBL5803173 0.78 KMT2A (0.67) PIK3CGKMT2ATLR9ATMMEN1
SCHEMBL29903456 0.78 KMT2A (0.67) PIK3CGKMT2ATLR9ATMMEN1
SCHEMBL30343134 0.76 KMT2A (0.53) PIK3CGKMT2ATLR9ATMMEN1
SCHEMBL31399917 0.76 KMT2A (0.53) PIK3CGKMT2ATLR9ATMMEN1
SCHEMBL11584180 0.76 KMT2A (0.53) PIK3CGKMT2ATLR9ATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670486-A Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety CIBA-GEIGY CORPORATION (US) 1987-06-02 US claimed
EP-0168343-B1 METAL COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING HIGH-MOLECULAR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1991-05-02 EP disclosed
EP-0169167-B1 PROCESS FOR DYEING HIGH-MOLECULAR ORGANIC MATERIALS, AND METAL COMPLEXES CIBA-GEIGY AG (CH) 1990-05-02 EP disclosed
US-4775747-A PIGMENTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1988-10-04 US disclosed
US-4670486-A Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety CIBA-GEIGY CORPORATION (US) 1987-06-02 US disclosed
US-4639477-A AZO DYES CIBA-GEIGY CORPORATION (US) 1987-01-27 US disclosed
EP-0185618-A2 Isoindolines, process for their manufacture and their use CIBA-GEIGY AG (CH) 1986-06-25 EP disclosed
EP-0169167-A2 Process for dyeing high-molecular organic materials, and metal complexes CIBA-GEIGY AG (CH) 1986-01-22 EP disclosed
EP-0168343-A2 Metal complexes, process for their preparation and their use in dyeing high-molecular organic materials CIBA-GEIGY AG (CH) 1986-01-15 EP disclosed
US-4400319-A Monoazo pigments containing heterocycles, and high-molecular organic materials dyed therewith CIBA-GEIGY CORPORATION (US) 1983-08-23 US disclosed
US-4220586-A FASTNESS TO LIGHT, OVER-LACQUERING, MIGRATION, WEATHERING, AND HEAT CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
US-4122117-A Indandione bis-azomethine pigments DAINIPPON INK & CHEMICALS, INC. (JP) 1978-10-24 US disclosed
US-4116959-A ISOINDOLINE PIGMENTS CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4088641-A YELLOW TO RED SHADES CIBA-GEIGY CORPORATION (US) 1978-05-09 US disclosed
US-4052410-A YELLOW, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1977-10-04 US disclosed
US-3979386-A YELLOW, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1976-09-07 US disclosed