SCHEMBL4586206

SCHEMBL4586206

Nc1ccc2nc3ccc(N)cc3nc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.67
MEN1 O00255 3/20 0.67
LMNA P02545 2/20 0.67
HTT P42858 2/20 0.67
F2 P00734 1/20 0.67
CHRM2 P08172 1/20 0.67
HTR1A P08908 1/20 0.67
ADRA2A P08913 1/20 0.67
ADORA3 P0DMS8 1/20 0.67
MAOA P21397 1/20 0.67
DRD1 P21728 1/20 0.67
ACHE P22303 1/20 0.67
PTGS1 P23219 1/20 0.67
SLC6A2 P23975 1/20 0.67
SLC6A4 P31645 1/20 0.67
OPRM1 P35372 1/20 0.67
DRD3 P35462 1/20 0.67
KDR P35968 1/20 0.67
SLC6A3 Q01959 1/20 0.67
KCNH2 Q12809 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922808 1.00 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
SCHEMBL3480837 1.00 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
Hydrochloric Acid SCHEMBL7566148 0.97 KMT2A (0.64) KMT2AMEN1LMNAHTTF2
SCHEMBL29903456 0.92 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
SCHEMBL5803173 0.92 KMT2A (0.67) KMT2AMEN1LMNAHTTF2
SCHEMBL31399917 0.85 KMT2A (0.53) KMT2AMEN1LMNAHTTF2
SCHEMBL30343134 0.85 KMT2A (0.53) KMT2AMEN1LMNAHTTF2
SCHEMBL1770021 0.85 KMT2A (0.53) KMT2AMEN1LMNAHTTF2
SCHEMBL11584180 0.85 KMT2A (0.53) KMT2AMEN1LMNAHTTF2
SCHEMBL9807438 0.85 PIK3CG (0.55) KMT2AMEN1LMNAHTTF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103598998-A Keratin fiber dyeing composition containing laccase and dyeing method thereof UNIV ANHUI 2014-02-26 CN claimed
EP-0891182-B1 ENZYME ASSISTED DYEING OF KERATINOUS FIBRES NOVOZYMES AS (DK) 2001-11-14 EP claimed
EP-0863950-B1 HAIR DYEING COMPOSITION NOVOZYMES AS (DK) 2001-10-10 EP claimed
EP-0865465-B1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVOZYMES AS (DK) 2001-05-30 EP claimed
CN-1216914-A Enzyme for dyeing keratinous fibres NOVO NORDISK AS (DK) 1999-05-19 CN claimed
EP-0865465-A1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVO NORDISK A/S (DK) 1998-09-23 EP claimed
WO-1997019999-A1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVO NORDISK A/S (DK) 1997-06-05 WO claimed
US-5428161-A Having at least one electron-withdrawing substituent on at least one of the groups attached to the amine groups at the 3- and 7-positions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-27 US claimed
EP-0339869-A2 Novel phenazine dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-02 EP claimed
JP-1313569-A None JP disclosed
EP-1353638-A4 NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING P & G CLAIROL INC (US) 2008-12-03 EP disclosed
EP-0973875-B1 STORAGE-STABLE LIQUID FORMULATION COMPRISING A LACCASE NOVOZYMES AS (DK) 2006-06-14 EP disclosed
EP-1357889-B1 NOVELS COUPLERS FOR USE IN OXIDATIVE HAIR DYEING P & G CLAIROL INC (US) 2006-04-05 EP disclosed
US-6908493-B2 Couplers for use in oxidative hair dyeing THE PROCTER & GAMBLE COMPANY (US) 2005-06-21 US disclosed
US-4647525-A Stabilized leuco phenazine dyes and their use in an imaging system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-03 US disclosed
EP-0124296-B1 THERMOGRAPHIC SYSTEM USING NAPHTHOYLATED LEUCO PHENAZINE DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-02-04 EP disclosed
EP-0181085-A1 Stabilized leuco phenazine dyes and their use in an imaging system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-05-14 EP disclosed
EP-0181085-A1 Stabilized leuco phenazine dyes and their use in an imaging system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-05-14 EP disclosed
US-4563415-A STABLE RED AND MAGENTA COLORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-01-07 US disclosed
EP-0124296-A1 Thermographic system using naphthoylated leuco phenazine dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-11-07 EP disclosed