SCHEMBL9807722

SCHEMBL9807722

CCCC(c1ccc(O)c(C2CCCCC2)c1)c1ccc(O)c(C2CCCCC2)c1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.49
BACE1 P56817 1/20 0.49
HSP90AA1 P07900 1/20 0.46
THRB P10828 2/20 0.40
CNR1 P21554 6/20 0.38
CNR2 P34972 5/20 0.38
ADRB2 P07550 1/20 0.38
ACMSD Q8TDX5 2/20 0.38
THRA P10827 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
ALDH1A1 P00352 1/20 0.35
BCHE P06276 1/20 0.35
TYR P14679 1/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27701919 0.90 NUDT1 (0.46) NUDT1BACE1HSP90AA1THRBCNR1
SCHEMBL4061776 0.89 NUDT1 (0.50) NUDT1BACE1HSP90AA1THRBCNR1
SCHEMBL28088196 0.89 NUDT1 (0.43) NUDT1BACE1HSP90AA1THRBCNR1
SCHEMBL8503276 0.88 NUDT1 (0.47) NUDT1BACE1HSP90AA1THRBCNR1
SCHEMBL10347780 0.88 NUDT1 (0.51) NUDT1BACE1HSP90AA1THRBCNR1
SCHEMBL3178564 0.86 NUDT1 (0.53) NUDT1BACE1HSP90AA1THRBADRB2
SCHEMBL3146459 0.82 NUDT1 (0.47) NUDT1BACE1HSP90AA1THRBADRB2
SCHEMBL11876985 0.82 GAA (0.51) NUDT1BACE1HSP90AA1THRBADRB2
SCHEMBL11873210 0.82 GAA (0.51) NUDT1BACE1HSP90AA1THRBADRB2
SCHEMBL11877058 0.81 NUDT1 (0.50) NUDT1BACE1HSP90AA1THRBACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5019548-A Basic Dye, Color Acceptor, Benzyloxyphenyl Methyl Sulfide KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-05-28 US disclosed
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed
EP-0373561-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-06-20 EP disclosed
EP-0358193-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-03-14 EP disclosed