Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28176328 | 0.97 | GNAI3 (0.47) | GNAI3GNAO1GNAI1DNM1ALDH1A1 | |
| SCHEMBL22383716 | 0.88 | TSHR (0.46) | DNM1ALDH1A1TSHREPHX1ACE2 | |
| SCHEMBL26553450 | 0.88 | TSHR (0.50) | ALDH1A1TSHREPHX1ACE2ANPEP | |
| SCHEMBL27283798 | 0.88 | TSHR (0.50) | ALDH1A1TSHREPHX1ACE2ANPEP | |
| SCHEMBL11507783 | 0.88 | TSHR (0.50) | ALDH1A1TSHREPHX1ACE2ANPEP | |
| SCHEMBL24936448 | 0.88 | TSHR (0.50) | ALDH1A1TSHREPHX1ACE2ANPEP | |
| SCHEMBL28166103 | 0.86 | TSHR (0.48) | GNAI3GNAO1GNAI1DNM1ALDH1A1 | |
| SCHEMBL21799678 | 0.86 | CA12 (0.43) | GNAI3GNAO1GNAI1DNM1ALDH1A1 | |
| SCHEMBL21799485 | 0.86 | CA12 (0.43) | GNAI3GNAO1GNAI1DNM1ALDH1A1 | |
| SCHEMBL21800006 | 0.86 | CA12 (0.43) | GNAI3GNAO1GNAI1DNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323163-B1 | SHIFT-FEEL DURABILITY ENHANCEMENT | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0323163-A1 | Shift-feel Durability enhancement | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4795583-A | FRICTION MODIFIER FOR AUTOMATIC TRANSMISSION FLUIDS CONTAINING AN ALIPHATIC TERTIARY AMINE, ALIPHATIC DIAMINE AND-OR N-SUBSTITUTED DIALKANOLAMINE | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-01-03 | — | — | US | disclosed |