Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | ATIC | P31939 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937442 | 0.85 | TTR (0.67) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL11815812 | 0.84 | TTR (0.61) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL6051313 | 0.84 | TTR (0.70) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL26638150 | 0.83 | TTR (0.59) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL5178110 | 0.81 | CYP1A2 (0.59) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL26743894 | 0.81 | TTR (0.61) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL29363198 | 0.80 | TTR (0.75) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL6242 | 0.80 | TTR (0.75) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL30233642 | 0.80 | TTR (0.75) | TTRAURKAAURKBCDK2CYP1A2 | |
| SCHEMBL153735 | 0.80 | NT5E (0.59) | TTRAURKAAURKBNT5EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241414-B1 | PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES | CIBA-GEIGY AG (CH) | 1991-05-08 | — | — | EP | disclosed |
| EP-0241414-A2 | Process for the preparation of 1:2 metal complex azo dyes | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |