Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | ATIC | P31939 | 2/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.42 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815812 | 0.98 | TTR (0.61) | TTRAURKAAURKBCYP1A2CDK2 | |
| SCHEMBL9808016 | 0.83 | TTR (0.62) | TTRAURKAAURKBCYP1A2CDK2 | |
| SCHEMBL6937442 | 0.82 | TTR (0.67) | TTRAURKAAURKBCYP1A2CDK2 | |
| SCHEMBL6051313 | 0.81 | TTR (0.70) | TTRAURKAAURKBCYP1A2CDK2 | |
| SCHEMBL30736514 | 0.80 | SLC7A11 (0.47) | TTRCDK2ALDH1A1APPTHRB | |
| SCHEMBL26638161 | 0.80 | SLC7A11 (0.47) | TTRCDK2ALDH1A1APPTHRB | |
| SCHEMBL127423 | 0.80 | TTR (0.72) | TTRAURKAAURKBCYP1A2CDK2 | |
| SCHEMBL28290095 | 0.80 | TTR (0.72) | TTRAURKAAURKBCYP1A2CDK2 | |
| SCHEMBL1121128 | 0.80 | TTR (0.72) | TTRAURKAAURKBCYP1A2CDK2 | |
| SCHEMBL7775179 | 0.79 | SENP2 (0.55) | TTRAURKAAURKBSUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230358677-A1 | Reversible Excited-State Photoacids and Photobases as Dynamic Fluorescence Sensors of Protonic Species | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-11-09 | — | — | US | claimed |
| US-20230358677-A1 | Reversible Excited-State Photoacids and Photobases as Dynamic Fluorescence Sensors of Protonic Species | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-11-09 | — | — | US | disclosed |