Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808069 | 0.95 | KDM4E (0.55) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL10917708 | 0.91 | KDM4E (0.53) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9808062 | 0.89 | TEAD1 (0.53) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL11345894 | 0.89 | KDM4E (0.51) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL10566292 | 0.89 | KDM4E (0.51) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL10737413 | 0.89 | KDM4E (0.56) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL10916274 | 0.89 | KDM4E (0.59) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9083039 | 0.89 | KDM4E (0.51) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7414719 | 0.88 | HDAC3 (0.54) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9580278 | 0.87 | HDAC3 (0.54) | KDM4EALDH1A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |