Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808182 | 0.92 | MAPT (0.53) | HTTHSD17B10MAPTRXFP1KMT2A | |
| SCHEMBL9808237 | 0.90 | KDM4E (0.55) | MEN1KMT2AMTNR1AMTNR1BTYR | |
| SCHEMBL9808286 | 0.84 | HTT (0.56) | HTTHSD17B10MAPTRXFP1KMT2A | |
| SCHEMBL9808054 | 0.83 | HTT (0.49) | HTTHSD17B10MAPTRXFP1KMT2A | |
| SCHEMBL9808191 | 0.82 | KDM4E (0.51) | HTTSMN1; SMN2MTNR1AMTNR1BKDM4E | |
| SCHEMBL9808195 | 0.81 | HTT (0.52) | HTTHSD17B10MAPTRXFP1KMT2A | |
| SCHEMBL9808250 | 0.80 | HDAC1 (0.54) | HTTHSD17B10MAPTMEN1KMT2A | |
| SCHEMBL9808190 | 0.80 | HDAC6 (0.49) | HTTMAPTMEN1KMT2AKDM4E | |
| SCHEMBL9808050 | 0.77 | HTT (0.56) | HTTHSD17B10RXFP1MEN1KMT2A | |
| SCHEMBL10441459 | 0.77 | GAA (0.55) | HTTHSD17B10MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |