Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808177 | 0.91 | HTT (0.59) | HTTALDH1A1PKMKDM4EPOLB | |
| SCHEMBL9808054 | 0.87 | HTT (0.49) | HTTALDH1A1PKMKDM4EPOLB | |
| SCHEMBL9808195 | 0.87 | HTT (0.52) | HTTALDH1A1PKMKDM4EPOLB | |
| SCHEMBL9808030 | 0.84 | HTT (0.52) | HTTALDH1A1PKMKDM4EPOLB | |
| SCHEMBL9808050 | 0.83 | HTT (0.56) | HTTALDH1A1PKMKDM4EPOLB | |
| SCHEMBL9808168 | 0.80 | ALDH1A1 (0.42) | HTTALDH1A1PKMKDM4EPOLB | |
| SCHEMBL9808060 | 0.78 | ALDH1A1 (0.53) | HTTALDH1A1PKMKDM4EPOLB | |
| SCHEMBL9808307 | 0.78 | HTT (0.53) | HTTALDH1A1PKMKDM4EPOLB | |
| SCHEMBL8387623 | 0.78 | TRPV1 (0.53) | MAPTHSD17B10HSP90AA1RXFP1TDP1 | |
| SCHEMBL19487332 | 0.78 | TEAD1 (0.48) | HTTALDH1A1PKMKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |