Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | YWHAG | P61981 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808202 | 0.91 | APP (0.41) | APPYWHAGMAPTGAAKDM4E | |
| SCHEMBL9808059 | 0.88 | GAA (0.40) | MAPTGAAKDM4EHTTCYP1A2 | |
| SCHEMBL9808204 | 0.87 | APP (0.50) | APPYWHAGMAPTPOLBALDH1A1 | |
| SCHEMBL9808292 | 0.86 | BCL2L11 (0.38) | MAPTGAAKDM4EALDH1A1PKM | |
| SCHEMBL9808295 | 0.84 | KDM4E (0.45) | MAPTGAAKDM4EPOLBALDH1A1 | |
| SCHEMBL9808029 | 0.83 | MEN1 (0.39) | MAPTGAAKDM4EPOLBHTT | |
| SCHEMBL9808040 | 0.83 | MEN1 (0.39) | MAPTGAAKDM4EPOLBHTT | |
| SCHEMBL3759191 | 0.81 | HSP90AA1 (0.44) | MAPTGAAPOLBALDH1A1PKM | |
| SCHEMBL9808284 | 0.81 | ATM (0.38) | MAPTGAAKDM4ECYP1A2GLA | |
| SCHEMBL9808022 | 0.81 | GABRA1 (0.44) | MAPTGAAPOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |