Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389466 | 0.89 | HPGD (0.50) | HPGDSMN1; SMN2 | |
| SCHEMBL9808027 | 0.89 | CNR2 (0.49) | HSP90AA1TDP1RXFP1HPGDKCNH2 | |
| SCHEMBL9808094 | 0.89 | TEAD1 (0.53) | HSP90AA1HPGDKCNH2KMT2ATEAD1 | |
| SCHEMBL9808287 | 0.88 | HPGD (0.50) | HSP90AA1TDP1RXFP1HPGDKCNH2 | |
| SCHEMBL9808042 | 0.86 | HPGD (0.56) | HSP90AA1TDP1RXFP1HPGDKCNH2 | |
| SCHEMBL8389664 | 0.86 | HPGD (0.50) | HPGDSMN1; SMN2 | |
| SCHEMBL9808050 | 0.85 | HTT (0.56) | HSP90AA1TDP1RXFP1HPGDKMT2A | |
| SCHEMBL9808036 | 0.85 | HPGD (0.62) | HSP90AA1HPGDKCNH2KMT2ATEAD1 | |
| SCHEMBL13751711 | 0.83 | CNR2 (0.45) | HSP90AA1TDP1RXFP1HPGDKCNH2 | |
| SCHEMBL8624633 | 0.83 | HPGD (0.50) | HPGDTEAD1YAP1TEAD4TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |