SCHEMBL9808210

SCHEMBL9808210

COc1cc(SCCOC(=O)C(C)Sc2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HSD17B2 P37059 2/20 0.41
FOS P01100 1/20 0.40
TTR P02766 1/20 0.40
JUN P05412 1/20 0.40
NR3C1 P04150 1/20 0.40
HSD17B1 P14061 1/20 0.40
MARS1 P56192 3/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
MEN1 O00255 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 2/20 0.40
AR P10275 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
NFKB1 P19838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9808093 0.87 EPHX1 (0.39) KDM4EPOLBNR3C1MEN1RAB9A
SCHEMBL9808224 0.85 EPHX1 (0.38) KDM4EPOLBGAATDP1LMNA
SCHEMBL9808103 0.84 KDM4E (0.48) KDM4EPOLBHDAC6HSD17B2FOS
SCHEMBL9808130 0.83 EPHX1 (0.37) KDM4ERAB9ATSHRALDH1A1TDP1
SCHEMBL9808041 0.81 KDM4E (0.46) KDM4EPOLBHDAC6HSD17B2FOS
SCHEMBL9808171 0.81 KDM4E (0.46) KDM4EPOLBHDAC6HSD17B2FOS
SCHEMBL9808295 0.80 KDM4E (0.45) KDM4EPOLBHDAC6HSD17B2SLC22A6
SCHEMBL9808055 0.80 KDM4E (0.45) KDM4EPOLBHDAC6HSD17B2SLC22A6
SCHEMBL9808201 0.80 EPHX1 (0.36) KDM4ETDP1LMNA
SCHEMBL9808114 0.76 HSP90AA1 (0.40) KDM4ETSHRALDH1A1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed
EP-0373561-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-06-20 EP disclosed