Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 4/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808224 | 0.93 | EPHX1 (0.38) | EPHX1LMNAKDM4EESR1THRA | |
| SCHEMBL9808093 | 0.84 | EPHX1 (0.39) | EPHX1LMNAKDM4EESR1HPGD | |
| SCHEMBL9808130 | 0.81 | EPHX1 (0.37) | EPHX1LMNAKDM4EESR1THRB | |
| SCHEMBL9808284 | 0.80 | ATM (0.38) | KDM4EESR1TDP1 | |
| SCHEMBL9808104 | 0.80 | LMNA (0.39) | EPHX1LMNAKDM4EESR1HPGD | |
| SCHEMBL9808210 | 0.80 | KDM4E (0.42) | LMNAKDM4ETDP1 | |
| SCHEMBL9750261 | 0.75 | ESR1 (0.44) | ESR1THRBCNR2TDP1 | |
| SCHEMBL9808114 | 0.74 | HSP90AA1 (0.40) | EPHX1LMNAKDM4EESR1HPGD | |
| SCHEMBL9808180 | 0.74 | APP (0.42) | ESR1TDP1 | |
| SCHEMBL6534989 | 0.73 | ESR1 (0.50) | ESR1THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |