Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.61 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.61 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474115 | 0.92 | ESR1 (0.73) | ESR1ESR2PDCD1CD274TYR | |
| Methane SCHEMBL21952122 | 0.90 | ESR1 (0.70) | ESR1ESR2PDCD1CD274TYR | |
| SCHEMBL1758100 | 0.88 | ESR1 (0.47) | ESR1ESR2PDCD1CD274TYR | |
| SCHEMBL9808121 | 0.85 | ESR1 (0.84) | ESR1ESR2PDCD1CD274TYR | |
| SCHEMBL920857 | 0.84 | ESR1 (0.67) | ESR1ESR2PDCD1CD274TYR | |
| SCHEMBL15232906 | 0.81 | ESR1 (0.84) | ESR1ESR2PDCD1CD274TYR | |
| SCHEMBL4059643 | 0.79 | ESR1 (0.58) | ESR1ESR2PDCD1CD274ADRA1A | |
| SCHEMBL29807688 | 0.79 | ESR1 (0.58) | ESR1ESR2PDCD1CD274ADRA1A | |
| SCHEMBL9755239 | 0.79 | ESR1 (0.59) | ESR1ESR2PDCD1CD274TYR | |
| SCHEMBL8031145 | 0.79 | ESR1 (0.80) | ESR1ESR2PDCD1CD274TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |