Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617976 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL5618350 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL9587583 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL5618390 | 0.71 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL7301253 | 0.66 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL5617725 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL9588107 | 0.65 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL18997369 | 0.63 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL2773193 | 0.62 | NPC1 (0.46) | ALDH1A1MAPTGAALMNAMEN1 | |
| SCHEMBL18997359 | 0.62 | KMT2A (0.55) | ALDH1A1KDM4EMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073563-A | Enzyme inhibitors, CNS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |