Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632418 | 0.90 | HSD17B10 (0.65) | NR1H4EPHX2FFAR1RXRARXRB | |
| SCHEMBL11884571 | 0.87 | NR1H4 (0.55) | NR1H4EPHX2FFAR1KEAP1RXRA | |
| SCHEMBL3687860 | 0.87 | PLK1 (0.41) | NR1H4EPHX2HSD17B10L3MBTL1CA2 | |
| SCHEMBL31158021 | 0.81 | NR1H4 (0.51) | NR1H4EPHX2FFAR1RXRARXRB | |
| SCHEMBL154857 | 0.81 | CYP4A11 (0.50) | CA1CA2 | |
| SCHEMBL1060928 | 0.81 | PLK1 (0.55) | L3MBTL1LMNA | |
| SCHEMBL9808692 | 0.80 | TAAR1 (0.45) | L3MBTL1CA1CA2 | |
| SCHEMBL3976669 | 0.80 | KMT2A (0.47) | HSD17B10L3MBTL1 | |
| SCHEMBL153898 | 0.79 | KMT2A (0.56) | NR1H4EPHX2RXRARXRBRXRG | |
| SCHEMBL195630 | 0.79 | RARB (0.57) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045573-A | Alkanophenones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-09-03 | — | — | US | claimed |
| EP-0216884-B1 | PHOTO-INITIATOR FOR THE PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS | MERCK PATENT GmbH (DE) | 1990-08-08 | — | — | EP | claimed |
| US-5045573-A | Alkanophenones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0216884-B1 | PHOTO-INITIATOR FOR THE PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS | MERCK PATENT GmbH (DE) | 1990-08-08 | — | — | EP | disclosed |
| US-4861916-A | Photoinitiators for photopolymerization of unsaturated systems | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-08-29 | — | — | US | disclosed |
| EP-0216884-A1 | PHOTO-INITIATOR FOR THE PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS. | MERCK PATENT GMBH (DE) | 1987-04-08 | — | — | EP | disclosed |
| WO-1986005778-A1 | PHOTO-INITIATORS FOR PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-10-09 | — | — | WO | disclosed |
| WO-1986005777-A1 | PHOTO-INITIATOR FOR THE PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-10-09 | — | — | WO | disclosed |