⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14838352 | 0.85 | THRB (0.31) | — | |
| SCHEMBL17936174 | 0.85 | THRB (0.31) | — | |
| SCHEMBL409546 | 0.80 | THRB (0.33) | — | |
| SCHEMBL15199305 | 0.78 | THRB (0.32) | — | |
| SCHEMBL9808807 | 0.77 | THRB (0.32) | — | |
| SCHEMBL13079443 | 0.77 | — | — | |
| SCHEMBL9808695 | 0.74 | — | — | |
| SCHEMBL27262180 | 0.73 | THRB (0.47) | — | |
| SCHEMBL14192749 | 0.72 | — | — | |
| SCHEMBL13524892 | 0.71 | THRB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311352-B1 | CATIONIC COMPLEXES OF TECHNETIUM-99M | AMERSHAM INTERNATIONAL plc (GB) | 1991-05-15 | — | — | EP | disclosed |
| US-4916214-A | RADIOLOGIC DIAGNOSIS | AMERSHAM INTERNATIONAL PLC. (GB) | 1990-04-10 | — | — | US | disclosed |
| WO-1989003388-A1 | CATIONIC COMPLEXES OF TECHNETIUM-99M | AMERSHAM INTERNATIONAL PLC (GB) | 1989-04-20 | — | — | WO | disclosed |
| EP-0311352-A1 | Cationic complexes of technetium-99m | AMERSHAM INTERNATIONAL plc (GB) | 1989-04-12 | — | — | EP | disclosed |