SCHEMBL9808744

SCHEMBL9808744

O=c1oc2ccccc2cc1N=C=S

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
TYR P14679 1/20 0.50
DAO P14920 1/20 0.50
AKR1B1 P15121 1/20 0.50
POLB P06746 1/20 0.50
MAOB P27338 6/20 0.47
ALDH1A1 P00352 6/20 0.47
KDM4E B2RXH2 5/20 0.47
RAB9A P51151 3/20 0.47
CA12 O43570 3/20 0.46
CA9 Q16790 3/20 0.46
CA1 P00915 2/20 0.46
CA3 P07451 1/20 0.46
TSHR P16473 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
GPR35 Q9HC97 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30175364 1.00 HPGD (0.50) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL2865289 0.85 SMN1; SMN2 (0.51) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL30266969 0.80 HPGD (0.58) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL8694950 0.79 HPGD (0.56) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL366591 0.75 CYP2A6 (0.44) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL29577532 0.73 HPGD (0.50) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL13461694 0.73 HPGD (0.50) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL4632815 0.72 HPGD (0.62) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL2229964 0.72 HPGD (0.56) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL1871083 0.71 HPGD (0.60) HPGDSMN1; SMN2TYRDAOAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11573238-B2 Means and methods for single molecule peptide sequencing VIB VZW (BE) 2023-02-07 US claimed
US-20200231956-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING UNIVERSITEIT GENT (BE) 2020-07-23 US claimed
US-12019076-B2 Means and methods for single molecule peptide sequencing VIB VZW (BE) 2024-06-25 US disclosed
US-11969268-B2 Systems and methods for home transdermal assessment of gastrointestinal function MEDIBEACON INC. (US) 2024-04-30 US disclosed
US-20230221329-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2023-07-13 US disclosed
EP-4185194-A1 SYSTEMS AND METHODS FOR HOME TRANSDERMAL ASSESSMENT OF GASTROINTESTINAL FUNCTION MediBeacon Inc. (US) 2023-05-31 EP disclosed
US-11573238-B2 Means and methods for single molecule peptide sequencing VIB VZW (BE) 2023-02-07 US disclosed
US-20220214354-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2022-07-07 US disclosed
EP-3948297-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2022-02-09 EP disclosed
US-20220022820-A1 SYSTEMS AND METHODS FOR HOME TRANSDERMAL ASSESSMENT OF GASTROINTESTINAL FUNCTION MEDIBEACON INC. 2022-01-27 US disclosed
WO-2020201350-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2020-10-08 WO disclosed
EP-3688152-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2020-08-05 EP disclosed
US-20200231956-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING UNIVERSITEIT GENT (BE) 2020-07-23 US disclosed
WO-2019063827-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2019-04-04 WO disclosed
EP-0176252-B1 ASSAY METHOD EMPLOYING FLUORESCENT CELL INCORPORATIVE DYE SYNTEX (U.S.A.) INC. (US) 1991-04-24 EP disclosed
US-4748129-A Assay method employing fluorescent cell incorporative dye SNYTEX (U.S.A.) INC. (US) 1988-05-31 US disclosed
EP-0176252-A2 Assay method employing fluorescent cell incorporative dye SYNTEX (U.S.A.) INC. (US) 1986-04-02 EP disclosed