Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30175364 | 0.85 | HPGD (0.50) | SMN1; SMN2HPGDTYRDAOAKR1B1 | |
| SCHEMBL9808744 | 0.85 | HPGD (0.50) | SMN1; SMN2HPGDTYRDAOAKR1B1 | |
| SCHEMBL30266969 | 0.82 | HPGD (0.58) | SMN1; SMN2HPGDTYRDAOAKR1B1 | |
| SCHEMBL8694950 | 0.80 | HPGD (0.56) | SMN1; SMN2HPGDTYRDAOAKR1B1 | |
| SCHEMBL1656932 | 0.77 | CYP2A6 (0.44) | SMN1; SMN2HPGDTYRDAOAKR1B1 | |
| SCHEMBL2229964 | 0.77 | HPGD (0.56) | SMN1; SMN2HPGDTYRDAOAKR1B1 | |
| SCHEMBL3052164 | 0.75 | KDM4E (0.55) | SMN1; SMN2HPGDMAOBKDM4EALDH1A1 | |
| SCHEMBL29589760 | 0.75 | CYP3A4 (0.48) | HPGDPOLBALDH1A1RAB9ACA1 | |
| SCHEMBL661077 | 0.75 | CYP3A4 (0.48) | HPGDPOLBALDH1A1RAB9ACA1 | |
| SCHEMBL29577532 | 0.75 | HPGD (0.50) | SMN1; SMN2HPGDTYRDAOAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2821430-A1 | Siloxane polymers with central polysiloxane polymer block with organofunctional residues, each comprising at least two bivalent groups selected from urea and/or carbamate groups and at least one UV/Vis chromophore as residue | Evonik Industries AG (DE) | 2015-01-07 | — | — | EP | claimed |
| US-20150004112-A1 | SILOXANE POLYMERS WITH A CENTRAL POLYSILOXANE POLYMER BLOCK WITH ORGANOFUNCTIONAL RADICALS EACH HAVING AT LEAST TWO BIVALENT GROUPS SELECTED FROM UREA AND/OR CARBAMATE GROUPS AND AT LEAST ONE UV/VIS CHROMOPHORE AS RADICAL | EVONIK INDUSTRIES AG (DE) | 2015-01-01 | — | — | US | claimed |
| EP-3280821-A2 | DETECTION OF ONE OR MORE PATHOGENS | Polyskope Labs (US) | 2018-02-14 | — | — | EP | disclosed |
| WO-2016164407-A2 | DETECTION OF ONE OR MORE PATHOGENS | POLYSKOPE LABS (US) | 2016-10-13 | — | — | WO | disclosed |
| US-9382254-B2 | Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis | GALAPAGOS NV (BE) | 2016-07-05 | — | — | US | disclosed |
| EP-2821430-A1 | Siloxane polymers with central polysiloxane polymer block with organofunctional residues, each comprising at least two bivalent groups selected from urea and/or carbamate groups and at least one UV/Vis chromophore as residue | Evonik Industries AG (DE) | 2015-01-07 | — | — | EP | disclosed |
| US-20150005275-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS. | GALAPAGOS NV (BE) | 2015-01-01 | — | — | US | disclosed |
| US-20150004112-A1 | SILOXANE POLYMERS WITH A CENTRAL POLYSILOXANE POLYMER BLOCK WITH ORGANOFUNCTIONAL RADICALS EACH HAVING AT LEAST TWO BIVALENT GROUPS SELECTED FROM UREA AND/OR CARBAMATE GROUPS AND AT LEAST ONE UV/VIS CHROMOPHORE AS RADICAL | EVONIK INDUSTRIES AG (DE) | 2015-01-01 | — | — | US | disclosed |
| CN-102281893-A | Vaccine strain of brachyspira hyodysenteriae | — | 2011-12-14 | — | — | CN | disclosed |
| WO-2010054437-A1 | VACCINE STRAINS OF BRACHYSPIRA HYODYSENTERIAE | SPIROGENE PTY LTD (AU) | 2010-05-20 | — | — | WO | disclosed |
| US-4877783-A | β-lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1989-10-31 | — | — | US | disclosed |
| EP-0071395-B1 | BETA-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| US-4609652-A | FORMAMIDYL DERIVATIVES OF AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1986-09-02 | — | — | US | disclosed |
| US-4539149-A | β-Lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1985-09-03 | — | — | US | disclosed |
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |
| US-4259506-A | SELECTIVELY DESTROYING WEEDS IN CROPS | PHILAGRO (FR) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150004112-A1 | SILOXANE POLYMERS WITH A CENTRAL POLYSILOXANE POLYMER BLOCK WITH ORGANOFUNCTIONAL RADICALS EACH HAVING AT LEAST TWO BIVALENT GROUPS SELECTED FROM UREA AND/OR CARBAMATE GROUPS AND AT LEAST ONE UV/VIS CHROMOPHORE AS RADICAL | CCNI, UBE2I, CCNB1 | SMN1; SMN2 2824/4885HPGD 2693/4885TYR 4283/4885 |
| US-20150005275-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS. | CFTR, ABCC3, ABCC5 | SMN1; SMN2 4483/4885HPGD 1909/4885TYR 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.