Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | F7 | P08709 | 6/20 | 0.34 |
| ▸ | F3 | P13726 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808780 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1F13A1THRB | |
| SCHEMBL3839180 | 0.88 | TRPV1 (0.44) | ALDH1A1MAPTPTGS1PPARGCYP19A1 | |
| SCHEMBL1293139 | 0.86 | TSHR (0.37) | PPARGPPARAPPARDTSHR | |
| SCHEMBL8568126 | 0.86 | TSHR (0.37) | ALDH1A1MAPTPTGS1F13A1THRB | |
| SCHEMBL17748854 | 0.86 | TSHR (0.37) | PPARGPPARAPPARDTSHR | |
| SCHEMBL8568120 | 0.86 | TSHR (0.37) | ALDH1A1MAPTPTGS1F13A1THRB | |
| SCHEMBL4623657 | 0.86 | TSHR (0.37) | PPARGPPARAPPARDTSHR | |
| SCHEMBL1293140 | 0.86 | TSHR (0.37) | PPARGPPARAPPARDTSHR | |
| SCHEMBL8568123 | 0.86 | TSHR (0.37) | ALDH1A1MAPTPTGS1F13A1THRB | |
| SCHEMBL4623652 | 0.86 | TSHR (0.37) | PPARGPPARAPPARDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235715-A2 | Tricyclic ketone, and its use as an aromatizing ingredient | FIRMENICH SA (CH) | 1987-09-09 | — | — | EP | claimed |
| EP-0235715-B1 | TRICYCLIC KETONE, AND ITS USE AS AN AROMATIZING INGREDIENT | FIRMENICH SA (CH) | 1991-05-15 | — | — | EP | disclosed |
| EP-0235715-A2 | Tricyclic ketone, and its use as an aromatizing ingredient | FIRMENICH SA (CH) | 1987-09-09 | — | — | EP | disclosed |