Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808910 | 0.92 | MAPT (0.48) | VCAM1MAPTMEN1KMT2ALMNA | |
| SCHEMBL23507272 | 0.89 | TSHR (0.49) | VCAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9808946 | 0.86 | VCAM1 (0.45) | VCAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9808949 | 0.86 | VCAM1 (0.45) | VCAM1MAPTMEN1KMT2AHTT | |
| SCHEMBL10505466 | 0.83 | HSD17B10 (0.45) | VCAM1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10452555 | 0.82 | PDE7A (0.50) | VCAM1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9808903 | 0.82 | MAPT (0.43) | VCAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9808904 | 0.81 | TDP1 (0.51) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11197700 | 0.81 | MAPK1 (0.50) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL10505223 | 0.80 | VCAM1 (0.51) | VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4956007-A | Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYOR RT. (HU) | 1990-09-11 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |